IRAK2 抗体
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北京 101111
Quick Overview for IRAK2 抗体 (ABIN7881321)
抗原
See all IRAK2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IRAK2 Antibody
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序列
- AKEICQKYLE KGAGRLPEDC AEALATAACL CLRR
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纯化方法
- Affinity purified
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免疫原
- Amino acids AKEICQKYLEKGAGRLPEDCAEALATAACLCLRR from the human protein were used as the immunogen for the IRAK2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IRAK2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IRAK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
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别名
- IRAK2
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背景
- Interleukin-1 receptor-associated kinase-like 2 is an enzyme that in humans is encoded by the IRAK2 gene. This gene is mapped to 3p25.3. IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.It binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
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UniProt
- O43187
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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