IL-3 抗体
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北京 101111
Quick Overview for IL-3 抗体 (ABIN7881307)
抗原
See all IL-3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- IL-3 Antibody / Interleukin 3 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant fragment of human Interleukin 3 protein was used as the immunogen for the IL-3 antibody.
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亚型
- IgG1, kappa
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anti-Interleukin 3 (IL-3) antibody
IL-3 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 (IL-3) (AA 101-166) antibodyIL-3 适用: 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 (IL-3) (AA 20-152) antibodyIL-3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 (IL-3) antibodyIL-3 适用: 大鼠 WB, ELISA, Neut 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 3 (IL-3) (AA 33-166) antibodyIL-3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 (IL-3) (AA 1-152) antibodyIL-3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 (IL-3) (AA 1-152) antibodyIL-3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 3 (IL-3) antibody (Biotin)IL-3 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 3 (IL-3) antibody (Biotin)IL-3 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 3 (IL-3) (AA 20-152) antibodyIL-3 适用: 人 WB, IHC, IF 宿主: 小鼠 Monoclonal 3B11 unconjugated
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应用备注
- Optimal dilution of the IL-3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the IL-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL-3 (Interleukin 3 (IL-3))
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别名
- IL-3
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背景
- Interleukin-3, or IL-3, is a pleiotropic cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL-3 not only supports growth of both pluripotent stem cells and the more differentiated committed progenitors, but it also stimulates the functional activity of some fully differentiated cells. IL-3 has also been shown to protect mast cells from undergoing apoptosis. IL-3 exerts its biological effects through a receptor which consists of a ligand-specific Alpha subunit and a signal transducing beta subunit common to the IL-3/IL-5/GM-CSF receptors. The carboxy terminus of the beta subunit has been shown to be necessary for activation of the MAP kinase signaling pathway. Although the IL-3 receptor has no intrinsic kinase activity, stimulation with IL-3 leads to tyrosine phosphorylation of the JAK/Tyk 2 family member, JAK2, which in turn activates and causes nuclear translocation of Stat5a and Stat5b.
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UniProt
- P08700
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途径
- JAK/STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy
抗原
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