IRF1 抗体
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北京 101111
Quick Overview for IRF1 抗体 (ABIN7881245)
抗原
See all IRF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IRF1 Antibody / Interferon regulatory factor 1
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Interferon regulatory factor 1 was used as the immunogen for the IRF1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IRF1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the IRF1 antibody at -20oC.
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- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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别名
- IRF1
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背景
- The protein encoded by the IRF1 gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [RefSeq]
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UniProt
- P10914
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途径
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
抗原
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