HSF1 抗体
Our Local Distributor
北京 101111
Quick Overview for HSF1 抗体 (ABIN7880977)
抗原
See all HSF1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Heat shock factor protein 1 Antibody / HSF1
-
序列
- KQLVHYTAQP LFLLDP
-
纯化方法
- Antigen affinity purified
-
免疫原
- Amino acids KQLVHYTAQPLFLLDP were used as the immunogen for the Heat shock factor protein 1 antibody.
-
亚型
- IgG
-
-
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (Biotin)
HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 Biotin
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (FITC)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 FITC
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (APC)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 APC
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (Atto 488)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 Atto 488
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (Atto 594)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 Atto 594
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (HRP)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 HRP
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (PerCP)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 PerCP
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (Atto 390)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 Atto 390
anti-Heat Shock Factor Protein 1 (HSF1) (AA 378-395) antibody (PE)HSF1 适用: 小鼠 WB, ELISA, IHC, IF, IP, ICC, GS 宿主: 大鼠 Monoclonal 10H8 PE
anti-Heat Shock Factor Protein 1 (HSF1) antibodyKD Validated HSF1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2715 unconjugated Recombinant Antibody
-
-
应用备注
- Optimal dilution of the Heat shock factor protein 1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the Heat shock factor protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- HSF1 (Heat Shock Factor Protein 1 (HSF1))
-
别名
- Heat shock factor protein 1
-
背景
- HSF1 (HEAT-SHOCK TRANSCRIPTION FACTOR 1), also called HEAT-SHOCK FACTOR 1, is a protein that in humans is encoded by the HSF1 gene. The product of HSF1 gene is a heat-shock transcription factor. The International Radiation Hybrid Mapping Consortium maps the HSF1 gene to chromosome 8. HSF1 exists as an inactive monomer in a complex with Hsp40/Hsp70 and Hsp90. Upon stress, such as elevated temperature, HSF1 is released from the chaperone complex and trimerizes. HSF1 is then transported into the nucleus where it is hyperphosphorylated and binds to DNA containing heat shock elements. HSF1's target genes include major inducible heat shock proteins such as Hsp72, and interestingly, noncoding RNA within Satellite III repeat regions. In a novel in vitro system human HSF1 can be activated by nonnative protein, heat, and geldanamycin. HSR1 is constitutively expressed in human and rodent cells and its homologs are functionally interchangeable. Furthermore, Hsf1-deficient mice had a longer free-running period than wildtype littermates.
-
UniProt
- Q00613
抗原
-
