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GZMB 抗体

This 兔 单克隆 antibody specifically detects GZMB in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7880924
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for GZMB 抗体 (ABIN7880924)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

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宿主

  • 106
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克隆类型

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单克隆

标记

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This GZMB antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

AAHC-7
  • 原理

    Granzyme B Antibody

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Granzyme B / GZMB was used as the immunogen for the Granzyme B antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Granzyme B antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the Granzyme B antibody at -20oC.
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    Granzyme B

    背景

    This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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