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GRID2 抗体

The 兔 多克隆 anti-GRID2 antibody (ABIN7880884) specifically detects GRID2 in WB, FACS 和 IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN7880884
发货至: 中国
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Quick Overview for GRID2 抗体 (ABIN7880884)

抗原

See all GRID2 抗体
GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

适用

  • 17
  • 15
  • 14
  • 2
人, 大鼠, 小鼠

宿主

  • 16
  • 2

克隆类型

  • 17
  • 1
多克隆

标记

  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRID2 antibody is un-conjugated

应用范围

  • 11
  • 8
  • 5
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  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    GRID2 Antibody

    序列

    KKDDEVFRTA VGDLNQN

    纯化方法

    Affinity purified

    免疫原

    Amino acids KKDDEVFRTAVGDLNQN from the human protein were used as the immunogen for the GRID2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the GRID2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the GRID2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    GRID2 (Glutamate Receptor, Ionotropic, delta 2 (GRID2))

    别名

    GRID2

    背景

    Glutamate receptor, ionotropic, delta 2, also known as GluD2 and GluR delta 2, is a protein that in humans is encoded by the GRID2 gene. The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.

    UniProt

    O43424

    途径

    Synaptic Membrane
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