GPBAR1 抗体
The 兔 多克隆 anti-GPBAR1 antibody is suitable to detect GPBAR1 in samples from 大鼠 和 小鼠. It has been validated for WB.
产品编号 ABIN7880835
发货至:
中国
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Quick Overview for GPBAR1 抗体 (ABIN7880835)
抗原
See all GPBAR1 抗体
GPBAR1
(G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
适用
大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
This GPBAR1 antibody is un-conjugated
应用范围
Western Blotting (WB)
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原理
- GPBAR1 Antibody / TGR5
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序列
- DQRYTAPWRA AAQR
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纯化方法
- Affinity purified
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免疫原
- Amino acids DQRYTAPWRAAAQR from the human protein were used as the immunogen for the GPBAR1 antibody.
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亚型
- IgG
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anti-G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) (C-Term) antibody
GPBAR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) (Cytoplasmic Domain) antibodyGPBAR1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the GPBAR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GPBAR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GPBAR1 (G Protein-Coupled Bile Acid Receptor 1 (GPBAR1))
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别名
- GPBAR1
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背景
- The G protein-coupled bile acid receptor 1 (GPBAR1) also known G-protein coupled receptor 19 (GPCR19), membrane-type receptor for bile acids (M-BAR) or TGR5 as is a protein that in humans is encoded by the GPBAR1 gene. This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
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UniProt
- Q8TDU6
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途径
- WNT signaling, Hormone Transport, Sensory Perception of Sound
抗原
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