FURIN 抗体
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北京 101111
Quick Overview for FURIN 抗体 (ABIN7880832)
抗原
See all FURIN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Furin Antibody
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Furin was used as the immunogen for the Furin antibody.
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亚型
- IgG
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anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 120-370) antibody
FURIN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 587-748) antibodyFURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 418-573) antibodyFURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (Internal Region) antibodyVerified FURIN 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyKD Validated FURIN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2160 unconjugated Recombinant Antibody
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 385-500) antibodyFURIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 578-734) antibodyFURIN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) (AA 520-701) antibodyFURIN 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyFURIN 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 1C3 unconjugated Recombinant Antibody
anti-Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN) antibodyFURIN 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal dilution of the Furin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the Furin antibody at -20oC.
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- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
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别名
- Furin
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背景
- The FURIN gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. The product of this gene is one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include proparathyroid hormone, transforming growth factor beta 1 precursor, proalbumin, pro-beta-secretase, membrane type-1 matrix metalloproteinase, beta subunit of pro-nerve growth factor and von Willebrand factor. It is also thought to be one of the proteases responsible for the activation of HIV envelope glycoproteins gp160 and gp140 and may play a role in tumor progression. This gene is located in close proximity to family member proprotein convertase subtilisin/kexin type 6 and upstream of the FES oncogene. [RefSeq]
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UniProt
- P09958
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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