FOXP1 抗体
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北京 101111
Quick Overview for FOXP1 抗体 (ABIN7880816)
抗原
See all FOXP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- FOXP1 Antibody
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序列
- DFDHDRDYED EPVNEDME
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纯化方法
- Affinity purified
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免疫原
- Amino acids DFDHDRDYEDEPVNEDME from the human protein were used as the immunogen for the FOXP1 antibody.
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亚型
- IgG
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anti-Forkhead Box P1 (FOXP1) (AA 481-677) antibody
FOXP1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6E4 unconjugated
anti-Forkhead Box P1 (FOXP1) (C-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 650-677) antibodyFOXP1 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (C-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 650-677), (C-Term) antibodyFOXP1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24604 unconjugated
anti-Forkhead Box P1 (FOXP1) (C-Term) antibodyFOXP1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 1-114) antibodyFOXP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E3-G11 unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 223-270) antibodyFOXP1 适用: 人, 小鼠, 大鼠, 兔, 犬, 马, 猴, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box P1 (FOXP1) (AA 627-677) antibodyFOXP1 适用: 人, 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Monoclonal BLR134H unconjugated Recombinant Antibody
anti-Forkhead Box P1 (FOXP1) (AA 541-677) antibodyFOXP1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the FOXP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the FOXP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FOXP1 (Forkhead Box P1 (FOXP1))
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别名
- FOXP1
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背景
- FOXP1 (forkhead box P1) is a gene that is necessary for the proper development of the brain and lung in mammals. It is a member of the large FOX family of transcription factors. This gene belongs to subfamily P of the forkhead box(FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region(3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. It was shown that the embryonic stem cell(ESC)-specific isoform of FOXP1 stimulates the expression of transcription factor genes required for pluripotency, including OCT4, NANOG, NR5A2, and GDF3, while concomitantly repressing genes required for ESC differentiation. This isoform also promotes the maintenance of ESC pluripotency and contributes to efficient reprogramming of somatic cells into induced pluripotent stem cells. These results reveal a pivotal role for an Alternative splicing event in the regulation of pluripotency through the control of critical ESC-specific transcriptional programs(2).
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UniProt
- Q9H334
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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