Recombinant EXOC2 抗体
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Quick Overview for Recombinant EXOC2 抗体 (ABIN7880755)
抗原
See all EXOC2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- EXOC2 Antibody / Exocyst complex component 2
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human EXOC2 was used as the immunogen for the EXOC2 antibody.
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亚型
- IgG
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anti-Exocyst Complex Component 2 (EXOC2) (N-Term) antibody
EXOC2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exocyst Complex Component 2 (EXOC2) antibodyKD Validated EXOC2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3030 unconjugated Recombinant Antibody
anti-Exocyst Complex Component 2 (EXOC2) (AA 1-220) antibodyEXOC2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exocyst Complex Component 2 (EXOC2) (AA 31-130) antibodyEXOC2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the EXOC2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the EXOC2 antibody at -20oC.
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- EXOC2 (Exocyst Complex Component 2 (EXOC2))
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别名
- EXOC2
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背景
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EXOC2 antibody detects exocyst complex component 2, a critical member of the octameric exocyst complex that regulates tethering of secretory vesicles to the plasma membrane. This protein, also known as Sec5, functions in exocytosis and polarized trafficking, ensuring cargo delivery to specific membrane domains. By organizing vesicle docking, EXOC2 plays a fundamental role in processes such as cell migration, epithelial polarity, and neurite outgrowth. Its interactions with Ral GTPases highlight its role in small GTPase-mediated trafficking control.
Research using EXOC2 antibody has connected this protein to cancer and neurological disorders. Overexpression of EXOC2 has been reported in several tumor types, where it may promote invasive behavior by enhancing targeted membrane addition and secretion of proteases. In neurons, altered exocyst function has been linked to impaired synaptic vesicle recycling and neurodevelopmental defects. Investigating EXOC2 therefore provides insight into both normal cellular organization and disease pathology.
Antibodies against EXOC2 have been validated in western blot, immunohistochemistry, and immunoprecipitation. These tools help characterize exocyst assembly, subcellular localization, and interactions with signaling proteins. High-specificity clones are particularly valuable for distinguishing EXOC2 from related exocyst components within large multiprotein complexes.
NSJ Bioreagents supplies this EXOC2 antibody for research applications in membrane trafficking, cancer biology, and neurobiology. Alternate names include exocyst complex component 2 antibody, Sec5 antibody, SEC5L1 antibody, and Sec5p antibody. -
UniProt
- Q96KP1
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途径
- Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
抗原
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