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ELANE 抗体

The 兔 单克隆 anti-ELANE antibody (Clone AOCI-5) (ABIN7880674) specifically detects ELANE in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7880674
发货至: 中国
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Quick Overview for ELANE 抗体 (ABIN7880674)

抗原

See all ELANE 抗体
ELANE (Elastase, Neutrophil Expressed (ELANE))

适用

  • 83
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宿主

  • 63
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克隆类型

  • 48
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单克隆

标记

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This ELANE antibody is un-conjugated

应用范围

  • 49
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Western Blotting (WB)

克隆位点

AOCI-5
  • 原理

    Neutrophil Elastase Antibody

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Neutrophil Elastase / ELANE was used as the immunogen for the Neutrophil Elastase antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Neutrophil Elastase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the Neutrophil Elastase antibody at -20oC.
  • 抗原

    ELANE (Elastase, Neutrophil Expressed (ELANE))

    别名

    Neutrophil Elastase

    背景

    Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. [RefSeq]

    UniProt

    P08246
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