DCLK1 抗体
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Quick Overview for DCLK1 抗体 (ABIN7880654)
抗原
See all DCLK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- DCLK1 Antibody / Doublecortin-like kinase 1
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Doublecortin-like kinase 1 was used as the immunogen for the DCLK1 antibody.
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亚型
- IgG
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anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibody
DCLK1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6H4 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 690-720) antibodyDCLK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB3161 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 143-381) antibodyDCLK1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyKD Validated DCLK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4805 unconjugated Recombinant Antibody
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 1-30), (N-Term) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3059 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibodyDCLK1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1751CT665-1-72 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F9 unconjugated
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应用备注
- Optimal dilution of the DCLK1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the DCLK1 antibody at -20oC.
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- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
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别名
- DCLK1
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背景
- The DCKL1 gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities. [RefSeq]
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UniProt
- O15075
抗原
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