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DKK2 抗体

The 小鼠 单克隆 anti-DKK2 antibody is suitable to detect DKK2 in samples from 人 和 小鼠. It has been validated for WB.
产品编号 ABIN7880625
发货至: 中国
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Quick Overview for DKK2 抗体 (ABIN7880625)

抗原

See all DKK2 抗体
DKK2 (Dickkopf 2 Homolog (DKK2))

适用

  • 55
  • 19
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 48
  • 6
  • 1
小鼠

克隆类型

  • 49
  • 6
单克隆

标记

  • 31
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DKK2 antibody is un-conjugated

应用范围

  • 41
  • 24
  • 22
  • 8
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)

克隆位点

1833CT856-7-20
  • 原理

    DKK2 Antibody

    纯化方法

    Protein G purified

    免疫原

    Recombinant human DKK2 was used as the immunogen for the DKK2 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the DKK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the DKK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    DKK2 (Dickkopf 2 Homolog (DKK2))

    别名

    DKK2

    背景

    Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). [UniProt]

    UniProt

    Q9UBU2

    途径

    WNT signaling
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