CDK4 抗体
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北京 101111
Quick Overview for CDK4 抗体 (ABIN7880539)
抗原
See all CDK4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CDK4 Antibody / Cyclin Dependent Kinase 4
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human CDK4 was used as the immunogen for the CDK4 antibody.
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亚型
- IgG
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anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 1-303) antibody
CDK4 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) antibodyKO Validated CDK4 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 273-305), (C-Term) antibodyCDK4 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB03154 unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 6-295) antibodyCDK4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 211-303) antibodyCDK4 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4F11 unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (N-Term) antibodyCDK4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) antibodyKD Validated CDK4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB745 unconjugated Recombinant Antibody
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 272-303), (C-Term) antibodyCDK4 适用: 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (N-Term) antibodyCDK4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 4 (CDK4) (AA 201-303) antibodyCDK4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CDK4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CDK4 antibody at -20oC.
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- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
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别名
- CDK4
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背景
- The protein encoded by the CDK4 gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [RefSeq]
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UniProt
- P11802
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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