CUBN 抗体
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Quick Overview for CUBN 抗体 (ABIN7880520)
抗原
See all CUBN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CUBN Antibody / Cubilin
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human Cubilin / CUBN was used as the immunogen for the CUBN antibody.
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亚型
- IgG
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anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) antibody
CUBN 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 51-150) antibodyCUBN 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (N-Term) antibodyCUBN 适用: 人 WB, IHC, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 98-207) antibodyCUBN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CUBN antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the CUBN antibody at -20oC.
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- CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
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别名
- CUBN
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背景
- Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface. [UniProt]
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UniProt
- O60494
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途径
- Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism
抗原
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