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Recombinant COL2 抗体

This 兔 单克隆 antibody specifically detects COL2 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7880474
发货至: 中国
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北京 101111
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Quick Overview for Recombinant COL2 抗体 (ABIN7880474)

抗原

See all COL2 抗体
COL2 (Collagen, Type II (COL2))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

  • 61
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单克隆

标记

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This COL2 antibody is un-conjugated

应用范围

  • 53
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

COL2A1-8810R
  • 原理

    Collagen II Antibody

    纯化方法

    Protein A/G affinity

    免疫原

    Bovine collagen type II (CII) was used as the immunogen for the Collagen II antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the Collagen II antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Collagen II antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    COL2 (Collagen, Type II (COL2))

    别名

    Collagen II

    背景

    The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.

    UniProt

    P02458
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