Recombinant COL2 抗体
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北京 101111
Quick Overview for Recombinant COL2 抗体 (ABIN7880473)
抗原
See all COL2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Collagen II Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Bovine collagen type II (CII) was used as the immunogen for the Collagen II antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the Collagen II antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Collagen II antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- COL2 (Collagen, Type II (COL2))
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别名
- Collagen II
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背景
- The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function. In cartilage, Collagen Type II constitutes the bulk of the fibril. Sensitization with Collagen Type II induces an erosive polyarthritis in rats, mice and higher primates which can resemble rheumatoid arthritis and relapsing polychrondritis.
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UniProt
- P02458
抗原
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