Recombinant CDSE1 抗体
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北京 101111
Quick Overview for Recombinant CDSE1 抗体 (ABIN7880471)
抗原
See all CDSE1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CSDE1 Antibody / Cold shock domain containing E1
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human CSDE1 was used as the immunogen for the CSDE1 antibody.
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亚型
- IgG
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anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (Internal Region) antibody
CDSE1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) antibodyKD Validated CDSE1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3505 unconjugated Recombinant Antibody
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) antibodyKD Validated CDSE1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3510 unconjugated Recombinant Antibody
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 670-765) antibodyCDSE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 433-630) antibodyCDSE1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 369-600) antibodyCDSE1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 1-245) antibodyCDSE1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 1-767) antibodyCDSE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 1-775) antibodyCDSE1 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CSDE1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the CSDE1 antibody at -20oC.
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- CDSE1 (Cold Shock Domain Containing E1, RNA-Binding (CDSE1))
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别名
- CSDE1
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背景
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CSDE1 antibody detects cold shock domain containing E1, an RNA-binding protein also known as UNR (upstream of N-ras). CSDE1 contains multiple cold shock domains that allow it to interact with RNA and regulate processes such as translation, RNA stability, and internal ribosome entry site (IRES)-mediated initiation. Its wide influence on gene expression positions CSDE1 as a key regulator of cellular adaptation and developmental programs.
Research using CSDE1 antibody has linked the protein to diverse biological processes. In embryogenesis, CSDE1 regulates translation of transcripts required for cell differentiation. In cancer, aberrant CSDE1 activity promotes tumor progression by stabilizing oncogenic mRNAs and enhancing their translation. Studies have shown that high CSDE1 expression is associated with melanoma, prostate cancer, and neuroblastoma, highlighting its role in malignancy. Conversely, CSDE1 also regulates apoptosis-related transcripts, underscoring its complex function in cell fate control.
CSDE1 has additional roles in viral biology, where it regulates the translation of viral RNAs that depend on IRES elements. Viruses such as poliovirus and hepatitis C exploit CSDE1 to enhance replication. Its dual function in host and viral RNA regulation makes it a subject of interest in infection research. In neurons, CSDE1 has been implicated in local translation within axons and dendrites, influencing synaptic plasticity and neuronal survival.
Antibodies against CSDE1 are validated for western blot, immunoprecipitation, immunofluorescence, and immunohistochemistry. These reagents allow detection of CSDE1 expression patterns, RNA-binding activities, and protein interactions. Clone-based antibodies provide high specificity for reproducible results across systems.
NSJ Bioreagents supplies this CSDE1 antibody for research into RNA regulation, cancer biology, and virology. -
UniProt
- O75534
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途径
- SARS-CoV-2 Protein Interactome
抗原
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