Recombinant CDSE1 抗体
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北京 101111
Quick Overview for Recombinant CDSE1 抗体 (ABIN7880470)
抗原
See all CDSE1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CSDE1 Antibody / Cold shock domain containing E1
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human CSDE1 was used as the immunogen for the CSDE1 antibody.
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亚型
- IgG
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anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (Internal Region) antibody
CDSE1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) antibodyKD Validated CDSE1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3505 unconjugated Recombinant Antibody
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) antibodyKD Validated CDSE1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3510 unconjugated Recombinant Antibody
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 670-765) antibodyCDSE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 433-630) antibodyCDSE1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 369-600) antibodyCDSE1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 1-245) antibodyCDSE1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 1-767) antibodyCDSE1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cold Shock Domain Containing E1, RNA-Binding (CDSE1) (AA 1-775) antibodyCDSE1 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CSDE1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the CSDE1 antibody at -20oC.
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- CDSE1 (Cold Shock Domain Containing E1, RNA-Binding (CDSE1))
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别名
- CSDE1
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背景
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CSDE1 antibody detects cold shock domain containing E1, an RNA binding protein encoded by the CSDE1 gene. CSDE1 contains five cold shock domains that mediate single stranded RNA binding, enabling regulation of mRNA stability, splicing, and translation. It associates with ribonucleoprotein complexes and influences the fate of transcripts involved in development, stress response, and tumorigenesis.
CSDE1 antibody is widely applied in RNA biology, cancer research, and developmental studies. CSDE1 promotes internal ribosome entry site (IRES) mediated translation of select mRNAs, enabling protein synthesis during conditions when cap dependent translation is impaired. It also regulates RNA turnover and processing through interactions with RNA binding proteins and decay machinery. By detecting CSDE1, researchers can evaluate how RNA binding proteins integrate post transcriptional control of gene expression.
Western blot assays detect CSDE1 protein bands in cytoplasmic fractions, while immunohistochemistry maps its distribution across epithelial and neuronal tissues. Immunofluorescence highlights punctate localization in ribonucleoprotein granules, consistent with functions in RNA storage and processing. These methods allow detailed characterization of CSDE1 expression and function.
CSDE1 plays important roles in tumorigenesis. In melanoma and other cancers, CSDE1 promotes oncogene expression and suppresses tumor suppressor translation. Elevated CSDE1 levels correlate with tumor progression, invasion, and metastasis. By applying CSDE1 antibody, scientists can investigate how post transcriptional regulation contributes to cancer biology and therapy resistance.
Beyond oncology, CSDE1 is implicated in embryonic development, neuronal differentiation, and stress adaptation. It influences neuronal polarity and axon growth, as well as cellular responses to hypoxia and nutrient deprivation. These broad functions highlight the research value of CSDE1 antibody across multiple biological fields.
CSDE1 antibody from NSJ Bioreagents provides dependable specificity for detecting this RNA binding regulator, supporting reliable analysis of RNA metabolism and translational control. -
UniProt
- O75534
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途径
- SARS-CoV-2 Protein Interactome
抗原
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