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Cofilin 2 抗体

This 小鼠 单克隆 antibody specifically detects Cofilin 2 in WB, IF, IHC (p), ICC 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7880465
发货至: 中国
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Quick Overview for Cofilin 2 抗体 (ABIN7880465)

抗原

See all Cofilin 2 (CFL2) 抗体
Cofilin 2 (CFL2)

适用

  • 55
  • 24
  • 10
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 48
  • 6
  • 1
小鼠

克隆类型

  • 49
  • 6
单克隆

标记

  • 38
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cofilin 2 antibody is un-conjugated

应用范围

  • 36
  • 21
  • 15
  • 15
  • 10
  • 8
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

8C13
  • 原理

    Cofilin 2 Antibody / CFL2

    序列

    KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKL

    纯化方法

    Affinity purified

    免疫原

    Amino acids KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKL were used as the immunogen for the Cofilin 2 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the Cofilin 2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Cofilin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Cofilin 2 (CFL2)

    别名

    Cofilin 2

    背景

    Cofilin 2 (muscle), also known as CFL2, is a protein which in humans is encoded by the CFL2 gene. It is mapped to 14q12. This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. And this protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

    UniProt

    Q9Y281

    途径

    Caspase Cascade in Apoptosis
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