Cofilin 2 抗体
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北京 101111
Quick Overview for Cofilin 2 抗体 (ABIN7880465)
抗原
See all Cofilin 2 (CFL2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Cofilin 2 Antibody / CFL2
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序列
- KDAIKKKFTG IKHEWQVNGL DDIKDRSTLG EKL
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纯化方法
- Affinity purified
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免疫原
- Amino acids KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKL were used as the immunogen for the Cofilin 2 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the Cofilin 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Cofilin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Cofilin 2 (CFL2)
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别名
- Cofilin 2
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背景
- Cofilin 2 (muscle), also known as CFL2, is a protein which in humans is encoded by the CFL2 gene. It is mapped to 14q12. This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. And this protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
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UniProt
- Q9Y281
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途径
- Caspase Cascade in Apoptosis
抗原
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