Claudin 16 抗体
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北京 101111
Quick Overview for Claudin 16 抗体 (ABIN7880445)
抗原
See all Claudin 16 (CLDN16) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Claudin 16 Antibody / CLDN16
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序列
- KSYSAPRTET AKMYAVDTRV
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纯化方法
- Affinity purified
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免疫原
- Amino acids KSYSAPRTETAKMYAVDTRV from the human protein were used as the immunogen for the Claudin 16 antibody.
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亚型
- IgG
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anti-Claudin 16 (CLDN16) (AA 1-73) antibody
CLDN16 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Claudin 16 (CLDN16) (AA 6-33), (N-Term) antibodyCLDN16 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB30098 unconjugated
anti-Claudin 16 (CLDN16) (AA 1-73) antibodyCLDN16 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人, 小鼠, 大鼠 WB, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (AA 13-41), (N-Term) antibodyCLDN16 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人, 小鼠, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (AA 6-33) antibodyCLDN16 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 16 (CLDN16) (C-Term) antibodyCLDN16 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Claudin 16 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Claudin 16 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Claudin 16 (CLDN16)
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别名
- Claudin 16
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背景
- Claudin-16 is a protein that in humans is encoded by the CLDN16 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.
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UniProt
- Q9Y5I7
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途径
- Hepatitis C
抗原
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