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Claudin 16 抗体 (N-Term)

CLDN16 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951545
发货至: 中国
  • 抗原 See all Claudin 16 (CLDN16) 抗体
    Claudin 16 (CLDN16)
    抗原表位
    • 15
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    AA 13-41, N-Term
    适用
    • 37
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 35
    • 2
    克隆类型
    • 36
    • 1
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Claudin 16 antibody is un-conjugated
    应用范围
    • 20
    • 18
    • 14
    • 13
    • 13
    • 13
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to CLDN16.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human CLDN16
    亚型
    Ig Fraction
    Top Product
    Discover our top product CLDN16 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Claudin 16 (CLDN16)
    别名
    Claudin-16 / CLDN16 (CLDN16 产品)
    别名
    CLDN16 antibody, HOMG3 antibody, PCLN1 antibody, claudin-16 antibody, Pcln1 antibody, claudin 16 antibody, CLDN16 antibody, Cldn16 antibody
    背景
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.Synonyms: CL-16, PCLN-1, PCLN1, Paracellin-1
    分子量
    33836 Da
    基因ID
    10686
    NCBI登录号
    NP_006571
    途径
    Hepatitis C
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