Recombinant CLIC4 抗体
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Quick Overview for Recombinant CLIC4 抗体 (ABIN7880409)
抗原
See all CLIC4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CLIC4 Antibody / Chloride intracellular channel protein 4
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human CLIC4 was used as the immunogen for the CLIC4 antibody.
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亚型
- IgG
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anti-Chloride Intracellular Channel 4 (CLIC4) (AA 1-253) antibody
CLIC4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyVerified CLIC4 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (AA 1-253) antibodyCLIC4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) antibodyKD Validated CLIC4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3465 unconjugated Recombinant Antibody
anti-Chloride Intracellular Channel 4 (CLIC4) antibodyKD Validated CLIC4 适用: 人 WB, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) antibodyCLIC4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14721 unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyCLIC4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (AA 104-253) antibodyCLIC4 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyCLIC4 适用: 人, 小鼠, 大鼠, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chloride Intracellular Channel 4 (CLIC4) (N-Term) antibodyCLIC4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CLIC4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the CLIC4 antibody at -20oC.
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- CLIC4 (Chloride Intracellular Channel 4 (CLIC4))
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别名
- CLIC4
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背景
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CLIC4 antibody targets chloride intracellular channel protein 4, a member of the CLIC family of proteins that function as intracellular chloride channels and signaling modulators. Unlike classical ion channels, CLIC4 can exist in both soluble and membrane-associated forms, transitioning between states to regulate chloride conductance. This protein is expressed across many tissues, including endothelial cells, immune cells, and epithelial cells, where it contributes to processes such as apoptosis, angiogenesis, and cellular stress responses.
Research using CLIC4 antibody has demonstrated its involvement in multiple pathological processes. CLIC4 is frequently upregulated during tissue remodeling and fibrotic diseases, where it influences transforming growth factor-beta (TGF-beta) signaling pathways. It has also been studied in the context of cancer, with evidence suggesting that CLIC4 contributes to tumor progression and metastasis through regulation of cell migration and invasion. In immune biology, CLIC4 has been implicated in the modulation of macrophage activation and inflammatory responses.
Validated clones for CLIC4 detection perform well in assays including western blot, immunohistochemistry, and immunofluorescence. Researchers use these antibodies to monitor subcellular localization, expression changes under stress conditions, and signaling outcomes tied to chloride channel activity. The versatility of CLIC4 in both membrane transport and cell signaling makes it a protein of interest in diverse fields of study.
NSJ Bioreagents offers this CLIC4 antibody to support investigations in cancer biology, fibrosis, and cellular signaling. Alternate names include chloride intracellular channel protein 4 antibody, CLIC4A antibody, MSTP046 antibody, HuH1 antibody, and DKFZp564F012 antibody. -
UniProt
- Q9Y696
抗原
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