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CCR5 抗体

The 兔 多克隆 anti-CCR5 antibody (ABIN7880398) specifically detects CCR5 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7880398
发货至: 中国
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Quick Overview for CCR5 抗体 (ABIN7880398)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

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宿主

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克隆类型

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  • 5
多克隆

标记

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This CCR5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    CCR5 Antibody

    序列

    EKFRNYLLVF FQKHIAKRFC K

    纯化方法

    Affinity purified

    免疫原

    Amino acids EKFRNYLLVFFQKHIAKRFCK from the human protein were used as the immunogen for the CCR5 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CCR5 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CCR5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CCR5

    背景

    C-C chemokine receptor type 5, also known as CCR5 or CD195, is a protein on the surface of white blood cells that is involved in the immune system as it acts as a receptor for chemokines. It is mapped to 3p21.31. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.

    UniProt

    P51681

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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