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Recombinant CHMP2B 抗体

This 兔 单克隆 antibody specifically detects CHMP2B in WB, IHC (p) 和 IP. It exhibits reactivity toward 人.
产品编号 ABIN7880390
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CHMP2B 抗体 (ABIN7880390)

抗原

See all CHMP2B 抗体
CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CHMP2B antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

克隆位点

25C36
  • 原理

    CHMP2B Antibody / Charged multivesicular body protein 2b

    纯化方法

    Affinity chromatography

    免疫原

    A peptide sequence specific to Charged multivesicular body protein 2b protein was used as the immunogen for the CHMP2B antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CHMP2B antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the CHMP2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))

    别名

    CHMP2B

    背景

    Charged multivesicular body protein 2b (CHMP2B) is a component of the endosomal sorting complex required for transport III (ESCRT-III). It plays a critical role in multivesicular body formation, membrane fission, and the sorting of ubiquitinated proteins for lysosomal degradation. CHMP2B is essential for maintaining proper endosomal trafficking and cellular protein homeostasis.

    Mutations in CHMP2B have been linked to neurodegenerative disorders, including frontotemporal dementia and amyotrophic lateral sclerosis. Research on CHMP2B helps elucidate mechanisms of vesicular transport, neuronal maintenance, and protein quality control, making it relevant in both basic and disease-focused studies.

    Using a high-quality CHMP2B antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A CHMP2B antibody from NSJ Bioreagents provides reliable and reproducible performance for studies in membrane trafficking, neurodegeneration, and cellular signaling. Selecting the right CHMP2B antibody is essential for obtaining consistent and meaningful results.

    UniProt

    Q9UQN3
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