CD46 抗体
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北京 101111
Quick Overview for CD46 抗体 (ABIN7880328)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD46 Antibody
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human CD46 was used as the immunogen for the CD46 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CD46 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the CD46 antibody at -20oC.
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- CD46
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别名
- CD46
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背景
- The protein encoded by the CD46 gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. [RefSeq]
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UniProt
- P15529
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途径
- Regulation of Actin Filament Polymerization
抗原
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