CD46 抗体
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北京 101111
Quick Overview for CD46 抗体 (ABIN7880327)
抗原
See all CD46 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD46 Antibody
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序列
- YRYLQRRKKK GTYLTDETHR EVKFTSL
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纯化方法
- Affinity purified
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免疫原
- Amino acids YRYLQRRKKKGTYLTDETHREVKFTSL from the human protein were used as the immunogen for the CD46 antibody.
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亚型
- IgG1
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anti-CD46 (CD46) (AA 40-320) antibody
CD46 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) antibodyKD Validated CD46 适用: 人 WB, FACS, ICC, IF (p) 宿主: 兔 Monoclonal 23GB5720 unconjugated Recombinant Antibody
anti-CD46 (CD46) (AA 317-343) antibodyCD46 适用: 人 WB, FACS, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 适用: 人, 小鼠 WB, FACS, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人 WB, IHC, ELISA 宿主: 兔 Monoclonal 7D12 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the CD46 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CD46 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CD46
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别名
- CD46
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背景
- CD46 complement regulatory protein also known as CD46 (cluster of differentiation 46) and Membrane Cofactor Protein is a protein which in humans is encoded by the CD46 gene. The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. And the encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.
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UniProt
- P15529
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途径
- Regulation of Actin Filament Polymerization
抗原
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