Recombinant CDX2 抗体
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北京 101111
Quick Overview for Recombinant CDX2 抗体 (ABIN7880213)
抗原
See all CDX2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- Recombinant CDX2 Antibody (azide and preservative free)
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纯化方法
- Protein A affinity chromatography
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免疫原
- A recombinant protein fragment from the human protein was used as the immunogen for the recombinant CDX2 antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the recombinant CDX2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant CDX2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- CDX2 (Caudal Type Homeobox 2 (CDX2))
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别名
- CDX2
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背景
- The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
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UniProt
- Q99626
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途径
- Peptide Hormone Metabolism, Stem Cell Maintenance
抗原
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