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Cathepsin B 抗体

This 兔 单克隆 antibody specifically detects Cathepsin B in WB. It exhibits reactivity toward 人.
产品编号 ABIN7880201
发货至: 中国
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中国
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Quick Overview for Cathepsin B 抗体 (ABIN7880201)

抗原

See all Cathepsin B (CTSB) 抗体
Cathepsin B (CTSB)

适用

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宿主

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克隆类型

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单克隆

标记

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This Cathepsin B antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

AAFO-3
  • 原理

    CTSB Antibody / Cathepsin B

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human Cathepsin B / CTSB was used as the immunogen for the CTSB antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CTSB antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the CTSB antibody at -20oC.
  • 抗原

    Cathepsin B (CTSB)

    别名

    CTSB

    背景

    The CTSB gene encodes a member of the C1 family of peptidases. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein has been associated with esophageal adenocarcinoma and other tumors. [RefSeq]

    UniProt

    P07858

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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