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Cadherin 5 抗体

This 山羊 多克隆 antibody specifically detects Cadherin 5 in ELISA, FACS 和 IF. It exhibits reactivity toward 人.
产品编号 ABIN7880132
发货至: 中国
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Quick Overview for Cadherin 5 抗体 (ABIN7880132)

抗原

See all Cadherin 5 (CDH5) 抗体
Cadherin 5 (CDH5)

适用

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宿主

  • 96
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山羊

克隆类型

  • 83
  • 50
多克隆

标记

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This Cadherin 5 antibody is un-conjugated

应用范围

  • 104
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ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
  • 原理

    Cadherin 5 Antibody / VE Cadherin

    序列

    KQARAHGKSV PE

    纯化方法

    Antigen affinity

    免疫原

    Amino acids KQARAHGKSVPE were used as the immunogen for this Cadherin 5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Cadherin 5 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    0.5 mg/mL in 1X TBS, pH 7.3, with 0.5 % BSA (US sourced) and 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store the Cadherin 5 antibody at -20oC.
  • 抗原

    Cadherin 5 (CDH5)

    别名

    Cadherin 5

    背景

    Cadherin 5 is primarily expressed in endothelial cells, where it plays a critical role in regulating cell-cell adhesion and maintaining the integrity of the vascular barrier. Through its interactions with other Cadherin molecules and cytoskeletal components, Cadherin 5 helps to form adherens junctions, specialized structures that hold adjacent cells together and facilitate cell communication. Research has shown that mutations or dysregulation of Cadherin 5 can lead to various pathologies, including vascular dysfunction, increased permeability of blood vessels, and impaired wound healing. In addition, Cadherin 5 has been implicated in the progression of cancer, as aberrant expression of this molecule can promote tumor invasion and metastasis.

    UniProt

    P33151

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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