Cadherin 5 抗体
Our Local Distributor
北京 101111
Quick Overview for Cadherin 5 抗体 (ABIN7880132)
抗原
See all Cadherin 5 (CDH5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Cadherin 5 Antibody / VE Cadherin
-
序列
- KQARAHGKSV PE
-
纯化方法
- Antigen affinity
-
免疫原
- Amino acids KQARAHGKSVPE were used as the immunogen for this Cadherin 5 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Optimal dilution of the Cadherin 5 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- 0.5 mg/mL in 1X TBS, pH 7.3, with 0.5 % BSA (US sourced) and 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot and store the Cadherin 5 antibody at -20oC.
-
-
- Cadherin 5 (CDH5)
-
别名
- Cadherin 5
-
背景
- Cadherin 5 is primarily expressed in endothelial cells, where it plays a critical role in regulating cell-cell adhesion and maintaining the integrity of the vascular barrier. Through its interactions with other Cadherin molecules and cytoskeletal components, Cadherin 5 helps to form adherens junctions, specialized structures that hold adjacent cells together and facilitate cell communication. Research has shown that mutations or dysregulation of Cadherin 5 can lead to various pathologies, including vascular dysfunction, increased permeability of blood vessels, and impaired wound healing. In addition, Cadherin 5 has been implicated in the progression of cancer, as aberrant expression of this molecule can promote tumor invasion and metastasis.
-
UniProt
- P33151
-
途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
-