BMP4 抗体
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北京 101111
Quick Overview for BMP4 抗体 (ABIN7880091)
抗原
See all BMP4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- BMP4 Antibody / Bone morphogenetic protein 4
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human BMP4 was used as the immunogen for the BMP4 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the BMP4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the BMP4 antibody at -20oC.
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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别名
- BMP4
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背景
- The BMP4 gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [RefSeq]
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UniProt
- P12644
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途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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