Recombinant ATRIP 抗体
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北京 101111
Quick Overview for Recombinant ATRIP 抗体 (ABIN7880026)
抗原
See all ATRIP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ATRIP Antibody / ATR-interacting protein
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纯化方法
- Affinity chromatography
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免疫原
- A peptide sequence specific to ATR-interacting protein was used as the immunogen for the ATRIP antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the ATRIP antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the ATRIP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ATRIP (ATR Interacting Protein (ATRIP))
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别名
- ATRIP
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背景
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ATR-interacting protein (ATRIP) is a key regulator of the DNA damage response, functioning as an essential partner of the ATR kinase. ATRIP binds to replication protein A-coated single-stranded DNA and recruits ATR to sites of DNA damage or replication stress, initiating checkpoint signaling that maintains genome stability.
ATRIP plays a vital role in coordinating cell cycle arrest and DNA repair processes in response to genotoxic stress. Defects in ATRIP function can compromise DNA damage checkpoint activation, leading to genomic instability and contributing to developmental abnormalities and disease susceptibility.
Using a high-quality ATRIP antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunoprecipitation. An ATRIP antibody from NSJ Bioreagents ensures consistent and reproducible results for studies in DNA repair, replication stress, and checkpoint signaling. Selecting the right ATRIP antibody is critical for advancing research in genome maintenance and disease mechanisms.
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UniProt
- Q8WXE1
抗原
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