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Recombinant ATRIP 抗体

The 兔 单克隆 anti-ATRIP antibody (Clone 26A07) (ABIN7880026) specifically detects ATRIP in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7880026
发货至: 中国
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北京 101111
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Quick Overview for Recombinant ATRIP 抗体 (ABIN7880026)

抗原

See all ATRIP 抗体
ATRIP (ATR Interacting Protein (ATRIP))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This ATRIP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

26A07
  • 原理

    ATRIP Antibody / ATR-interacting protein

    纯化方法

    Affinity chromatography

    免疫原

    A peptide sequence specific to ATR-interacting protein was used as the immunogen for the ATRIP antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ATRIP antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the ATRIP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    ATRIP (ATR Interacting Protein (ATRIP))

    别名

    ATRIP

    背景

    ATR-interacting protein (ATRIP) is a key regulator of the DNA damage response, functioning as an essential partner of the ATR kinase. ATRIP binds to replication protein A-coated single-stranded DNA and recruits ATR to sites of DNA damage or replication stress, initiating checkpoint signaling that maintains genome stability.

    ATRIP plays a vital role in coordinating cell cycle arrest and DNA repair processes in response to genotoxic stress. Defects in ATRIP function can compromise DNA damage checkpoint activation, leading to genomic instability and contributing to developmental abnormalities and disease susceptibility.

    Using a high-quality ATRIP antibody enables accurate detection in applications such as western blot, immunohistochemistry, and immunoprecipitation. An ATRIP antibody from NSJ Bioreagents ensures consistent and reproducible results for studies in DNA repair, replication stress, and checkpoint signaling. Selecting the right ATRIP antibody is critical for advancing research in genome maintenance and disease mechanisms.

    UniProt

    Q8WXE1
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