ABCA4 抗体
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北京 101111
Quick Overview for ABCA4 抗体 (ABIN7880018)
抗原
See all ABCA4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- ABCA4 Antibody / ATP-binding cassette sub-family A member 4
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序列
- KQQTESHDLP LHPR
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纯化方法
- Antigen affinity
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免疫原
- Amino acids KQQTESHDLPLHPR were used as the immunogen for this ABCA4 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the ABCA4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- 0.5 mg/mL in 1X TBS, pH 7.3, with 0.5 % BSA (US sourced) and 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store the ABCA4 antibody at -20oC.
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- ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
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别名
- ABCA4
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背景
- The ABCA4 protein is a transporter molecule responsible for moving retinal molecules across cell membranes in the eye and may have a broader impact on neurological processes. Research has shown that this protein is not restricted to the eyes, but is also present in various regions of the brain. ABCA4 plays a role in the maintenance of lipid homeostasis in the central nervous system. Lipids are essential components of cell membranes and are crucial for neuronal function. Disruptions in lipid metabolism have been implicated in numerous neurological disorders, including Alzheimer's disease and Parkinson's disease. ABCA4 has been found to interact with other proteins involved in synaptic transmission and neuronal signaling. This suggests that the protein may play a role in modulating communication between neurons, which is essential for cognitive function.
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UniProt
- P16284
抗原
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