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ABCA4 抗体 (AA 2250-2263)

Verified ABCA4 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN343052
发货至: 中国
  • 抗原 See all ABCA4 抗体
    ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2250-2263
    适用
    • 20
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 19
    • 5
    • 1
    山羊
    克隆类型
    • 21
    • 4
    多克隆
    标记
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCA4 antibody is un-conjugated
    应用范围
    • 16
    • 9
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    原理
    ABCA4
    序列
    KQQTESHDLP LHPR
    交叉反应
    犬, 人
    纯化方法
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    质量等级
    Verified
    免疫原
    Synthetic peptide C-KQQTESHDLPLHPR from the C-terminus of human ABCA4 (NP_000341.2).
    Type of Immunogen: Synthetic peptide
    亚型
    IgG
  • 应用备注
    Peptide ELISA: antibody detection limit dilution 1:128000.
    说明

    Immunofluorescence: Strong expression of the protein seen in the Endoplasmic Reticulum of MCF7 and HeLa cells. Recommended concentration: 10μg/ml. This antibody has been successfully used in IF on Mouse, PMID: 32371886.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Minimize freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • McClements, Barnard, Issa, MacLaren: "Assessment of AAV Dual Vector Safety in theAbca4-/- Mouse Model of Stargardt Disease." in: Translational vision science & technology, Vol. 9, Issue 7, pp. 20, (2020) (PubMed).

    McClements, Barnard, Singh, Charbel Issa, Jiang, Radu, MacLaren: "An AAV Dual Vector Strategy Ameliorates the Stargardt Phenotype in Adult Abca4-/- Mice." in: Human gene therapy, Vol. 30, Issue 5, pp. 590-600, (2019) (PubMed).

    Lenis, Hu, Ng, Jiang, Sarfare, Lloyd, Esposito, Samuel, Jaworski, Bok, Finnemann, Radeke, Redmond, Travis, Radu: "Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 47, pp. E11120-E11127, (2019) (PubMed).

  • 抗原
    ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))
    别名
    ABCA4 (ABCA4 产品)
    别名
    ABC10 antibody, ABCR antibody, ARMD2 antibody, CORD3 antibody, FFM antibody, RMP antibody, RP19 antibody, STGD antibody, STGD1 antibody, AW050280 antibody, Abc10 antibody, Abcr antibody, D430003I15Rik antibody, RmP antibody, abcr antibody, ffm antibody, rmp antibody, rp19 antibody, stgd antibody, abc10 antibody, armd2 antibody, cord3 antibody, stgd1 antibody, zgc:91823 antibody, ATP binding cassette subfamily A member 4 antibody, ATP-binding cassette, sub-family A (ABC1), member 4 antibody, ATP binding cassette subfamily A member 4 L homeolog antibody, ATP-binding cassette, sub-family A (ABC1), member 4a antibody, ABCA4 antibody, Abca4 antibody, abca4 antibody, abca4.L antibody, abca4a antibody
    背景
    ABCA4, ATP-binding cassette, sub-family A (ABC1), member 4, ABC10, ABCR, ARMD2, CORD3, DKFZp781N1972, FFM, RMP, RP19, STGD, STGD1, ATP binding cassette transporter, ATP-binding cassette, sub-family A member 4, ATP-binding transporter, retina-specific, ret
    基因ID
    24
    NCBI登录号
    NP_000341
    UniProt
    P78363
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