ALOX5 抗体
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北京 101111
Quick Overview for ALOX5 抗体 (ABIN7879995)
抗原
See all ALOX5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- 5-Lipoxygenase Antibody / ALOX5
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human 5-Lipoxygenase / ALOX5 was used as the immunogen for the 5-Lipoxygenase antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the 5-Lipoxygenase antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the 5-Lipoxygenase antibody at -20oC.
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- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
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别名
- 5-Lipoxygenase
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背景
- The ALOX5 gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. [RefSeq]
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UniProt
- P09917
抗原
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