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ALDH2 抗体

This 兔 单克隆 antibody specifically detects ALDH2 in WB. It exhibits reactivity toward 人.
产品编号 ABIN7879940
发货至: 中国
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Quick Overview for ALDH2 抗体 (ABIN7879940)

抗原

See all ALDH2 抗体
ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

适用

  • 92
  • 39
  • 37
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 68
  • 21
  • 3

克隆类型

  • 57
  • 35
单克隆

标记

  • 50
  • 10
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
This ALDH2 antibody is un-conjugated

应用范围

  • 78
  • 44
  • 35
  • 25
  • 23
  • 22
  • 13
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  • 3
  • 2
Western Blotting (WB)

克隆位点

AFOI-1
  • 原理

    ALDH2 Antibody / Aldehyde dehydrogenase 2

    纯化方法

    Affinity purified

    免疫原

    A synthetic peptide specific to human ALDH2 was used as the immunogen for the ALDH2 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ALDH2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the ALDH2 antibody at -20oC.
  • 抗原

    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

    别名

    ALDH2

    背景

    This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [RefSeq]

    UniProt

    P05091
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