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Recombinant ACAT1 抗体

This 兔 单克隆 antibody specifically detects ACAT1 in WB 和 IP. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7879856
发货至: 中国
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Quick Overview for Recombinant ACAT1 抗体 (ABIN7879856)

抗原

See all ACAT1 抗体
ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

抗体类型

Recombinant Antibody

适用

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  • 3
  • 3
  • 3
  • 2
  • 2
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 76
  • 7
  • 6

克隆类型

  • 65
  • 24
单克隆

标记

  • 51
  • 8
  • 3
  • 2
  • 2
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  • 2
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  • 2
  • 1
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This ACAT1 antibody is un-conjugated

应用范围

  • 59
  • 39
  • 32
  • 22
  • 16
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  • 11
  • 9
  • 4
  • 3
  • 2
Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

29A55
  • 原理

    ACAT1 Antibody / Acetyl-CoA acetyltransferase

    纯化方法

    Affinity chromatography

    免疫原

    A synthetic peptide specific to human Acetyl-CoA acetyltransferase protein was used as the immunogen for the ACAT1 Antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the ACAT1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the ACAT1 antibody at -20oC.
  • 抗原

    ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

    别名

    ACAT1

    背景

    The Acetyl-CoA acetyltransferase protein, also called ACAT1, is an enzyme that catalyzes the conversion of Acetyl-CoA to acetoacetyl-CoA. This reaction is a key step in the fatty acid beta-oxidation pathway, which is essential for the breakdown of fatty acids and the production of energy. Additionally, ACAT1 plays a critical role in ketogenesis, a process that occurs during times of fasting or low carbohydrate intake. The structure of the Acetyl-CoA acetyltransferase protein is highly conserved among different species, indicating its importance in cellular metabolism. This enzyme contains an active site where the catalytic reaction takes place, as well as binding sites for its substrate and cofactors. The precise mechanism by which Acetyl-CoA is converted to acetoacetyl-CoA by this enzyme involves a series of chemical reactions that involve the transfer of acetyl groups.

    UniProt

    P24752
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