CDK7 抗体 (pThr170)
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Quick Overview for CDK7 抗体 (pThr170) (ABIN7879782)
抗原
See all CDK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr170
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原理
- Phospho-CDK7 Antibody (pT170)
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纯化方法
- Antigen affinity purified
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免疫原
- A synthetic peptide corresponding the amino acids surrounding phosphorylated T170 was used as the immunogen for the phosph-CDK7 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the phospho-CDK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the phospho-CDK7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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别名
- CDK7
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背景
- The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
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UniProt
- P50613
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途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
抗原
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