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CDK7 抗体 (pThr170)

The 兔 多克隆 anti-CDK7 antibody is suitable to detect CDK7 in samples from 人 和 小鼠. It has been validated for WB, IHC (p) 和 DB.
产品编号 ABIN7879782
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDK7 抗体 (pThr170) (ABIN7879782)

抗原

See all CDK7 抗体
CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This CDK7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)
  • 抗原表位

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    pThr170

    原理

    Phospho-CDK7 Antibody (pT170)

    纯化方法

    Antigen affinity purified

    免疫原

    A synthetic peptide corresponding the amino acids surrounding phosphorylated T170 was used as the immunogen for the phosph-CDK7 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the phospho-CDK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-CDK7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

    别名

    CDK7

    背景

    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

    UniProt

    P50613

    途径

    Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
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