MECP2 抗体 (pSer423)
Our Local Distributor
北京 101111
Quick Overview for MECP2 抗体 (pSer423) (ABIN7879743)
抗原
See all MECP2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer423
-
原理
- Phospho-MeCP2 Antibody (pS423)
-
纯化方法
- Antigen affinity purified
-
免疫原
- A synthetic peptide corresponding the amino acids surrounding phosphorylated S423 was used as the immunogen for the phospho-MeCP2 antibody.
-
亚型
- IgG
-
-
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 7-148) antibody
MECP2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 8H4A5B9 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibodyMECP2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B11 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (pSer423) antibodyMECP2 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29261 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-486) antibodyMECP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 400-428) antibodyMECP2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB25959 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (C-Term) antibodyMECP2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 58-87), (N-Term) antibodyMECP2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27934 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 81-170) antibodyMECP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4B6 unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (N-Term) antibodyMECP2 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Methyl CpG Binding Protein 2 (MECP2) (AA 1-100) antibodyMECP2 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the phospho-MeCP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the phospho-MeCP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
-
别名
- MeCP2
-
背景
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
-
UniProt
- P51608
-
途径
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
抗原
-
