MSK1 抗体 (pSer376)
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Quick Overview for MSK1 抗体 (pSer376) (ABIN7879734)
抗原
See all MSK1 (RPS6KA5) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer376
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原理
- Phospho-MSK1 Antibody (pS376)
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纯化方法
- Affinity purified
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免疫原
- A synthetic peptide specific to human MSK1 / RPS6KA5 (surrounding pS376) was used as the immunogen for the phospho-MSK1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the phospho-MSK1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the phospho-MSK1 antibody at -20oC.
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- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
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别名
- MSK1
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背景
- Mitogen and stress activated protein kinase 1,' also called RPS6KA5, is a serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. [UniProt]
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UniProt
- O75582
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途径
- MAPK Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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