电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

UBE2C 抗体 (full length)

The 小鼠 单克隆 anti-UBE2C antibody is suitable to detect UBE2C in samples from 人. It has been validated for ELISA 和 IHC (p).
产品编号 ABIN7879293
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for UBE2C 抗体 (full length) (ABIN7879293)

抗原

See all UBE2C 抗体
UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

适用

  • 80
  • 15
  • 13
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 62
  • 17
  • 1
小鼠

克隆类型

  • 59
  • 20
  • 1
单克隆

标记

  • 45
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UBE2C antibody is un-conjugated

应用范围

  • 63
  • 38
  • 21
  • 13
  • 13
  • 13
  • 7
  • 6
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CPTC-UBE2C-1
  • 抗原表位

    • 15
    • 11
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    UBE2C Antibody / UBCH10 (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Recombinant human full-length protein was used as the immunogen for the UBE2C antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the UBE2C antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the UBE2C antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

    别名

    UBE2C

    背景

    The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ubconjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2C, also designated UBCH10 in human, is an E2 ubiquitin conjugating enzyme for the anaphase promoting complex (APC), which coordinates mitosis and G1 by sequentially promoting the degradation of key cell-cycle regulators. UBE2C is overexpressed in many different types of cancers and may be a potential therapeutic target.

    UniProt

    O00762

    途径

    Ubiquitin Proteasome Pathway
You are here: