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NUMA1 抗体 (pSer395) (Cy5)

This Cy5-conjugated 兔 多克隆 anti-NUMA1 antibody specifically detects NUMA1 in IF (p) 和 IF (cc). The antibody is reactive with 人 samples.
产品编号 ABIN744447
发货至: 中国
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Quick Overview for NUMA1 抗体 (pSer395) (Cy5) (ABIN744447)

抗原

See all NUMA1 抗体
NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This NUMA1 antibody is conjugated to Cy5

应用范围

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Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    pSer395

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human NuMA around the phosphorylation site of Ser395

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

    别名

    NuMA

    背景

    Synonyms: NUMA 1, NuMA protein, NUMA1, SP H antigen, Structural nuclear protein, Centrophilin stabilizes mitotic spindle in mitotic cells, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein.

    Background: NuMA (Nuclear Mitotic Apparatus Protein) is an intranuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200 kDa during apoptosis.

    基因ID

    4926

    途径

    Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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