Tropomyosin 抗体 (full length)
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北京 101111
Quick Overview for Tropomyosin 抗体 (full length) (ABIN7879209)
抗原
See all Tropomyosin (TPM1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Alpha Tropomyosin Antibody / Tropomyosin-1 / TPM1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length protein was used as the immunogen for the Alpha Tropomyosin antibody.
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亚型
- IgG1
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anti-Tropomyosin 1 (Alpha) (TPM1) (AA 1-245) antibody
TPM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyKD Validated TPM1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2545 unconjugated Recombinant Antibody
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠, 斑马鱼, 兔, Cow, 犬, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) antibodyTPM1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Tropomyosin 1 (Alpha) (TPM1) (N-Term) antibodyTPM1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Alpha Tropomyosin antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Alpha Tropomyosin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))
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别名
- Alpha Tropomyosin
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背景
- Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind actin filaments and function to modulate Actin-myosin interaction and stabilize actin filament structure. Tropomyosin Alpha is encoded by the TPM1 gene, which maps to human chromosome 15q22.2 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Tropomyosin b is encoded by the TPM2 gene, which maps to human chromosome 9p13.3 and undergoes alternative splicing to generate three isoforms, including skeletal muscle (isoform 1), non-muscle/fibroblast TM36/epithelial TMe1 (isoform 2) and non-muscle (isoform 3). Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with actin filaments may increase the rigidity of actin filaments. Tropomyosin also interacts with caldesmon to regulate smooth muscle contraction.
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UniProt
- P04268
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途径
- Regulation of Actin Filament Polymerization
抗原
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