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TMPRSS2 抗体 (full length)

This 小鼠 单克隆 antibody specifically detects TMPRSS2 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7879196
发货至: 中国
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Quick Overview for TMPRSS2 抗体 (full length) (ABIN7879196)

抗原

See all TMPRSS2 抗体
TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

适用

  • 54
  • 22
  • 14
  • 1
  • 1
  • 1

宿主

  • 42
  • 13
  • 1
小鼠

克隆类型

  • 33
  • 23
单克隆

标记

  • 39
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This TMPRSS2 antibody is un-conjugated

应用范围

  • 41
  • 27
  • 16
  • 13
  • 12
  • 11
  • 8
  • 5
  • 2
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TMPRSS2-7410
  • 抗原表位

    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    原理

    TMPRSS2 Antibody / Transmembrane protease serine 2

    纯化方法

    Protein A/G affinity

    免疫原

    Recombinant full-length human TMPRSS2 protein was used as the immunogen for the TMPRSS2 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the TMPRSS2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the TMPRSS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

    别名

    TMPRSS2

    背景

    Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland. TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain. TMPRSS2 is expressed as a full length form and a cleaved protease domain and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis.

    UniProt

    O15393

    途径

    SARS-CoV-2 Protein Interactome
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