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Recombinant TCP1 alpha/CCTA 抗体 (full length)

The 兔 单克隆 anti-TCP1 alpha/CCTA antibody (Clone TP63-1423R) (ABIN7879126) specifically detects TCP1 alpha/CCTA in IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7879126
发货至: 中国
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Quick Overview for Recombinant TCP1 alpha/CCTA 抗体 (full length) (ABIN7879126)

抗原

See all TCP1 alpha/CCTA (TCP1) 抗体
TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

抗体类型

Recombinant Antibody

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This TCP1 alpha/CCTA antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TP63-1423R
  • 抗原表位

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    full length

    原理

    Recombinant p63 Antibody / Rabbit Monoclonal

    纯化方法

    Protein A affinity chromatography

    免疫原

    Full-length human recombinant protein was used as the immunogen for the recombinant p63 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant p63 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant p63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

    别名

    p63

    背景

    P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

    UniProt

    Q9H3D4
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