Recombinant TCP1 alpha/CCTA 抗体 (full length)
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Quick Overview for Recombinant TCP1 alpha/CCTA 抗体 (full length) (ABIN7879125)
抗原
See all TCP1 alpha/CCTA (TCP1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- Recombinant p63 Antibody / Rabbit Monoclonal (azide and preservative free)
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纯化方法
- Protein A affinity chromatography
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免疫原
- Full-length human recombinant protein was used as the immunogen for the recombinant p63 antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the recombinant p63 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant p63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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别名
- p63
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背景
- P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
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UniProt
- Q9H3D4
抗原
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