Recombinant TCP1 alpha/CCTA 抗体 (full length)
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Quick Overview for Recombinant TCP1 alpha/CCTA 抗体 (full length) (ABIN7879124)
抗原
See all TCP1 alpha/CCTA (TCP1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- full length
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原理
- Recombinant p63 Antibody / Rabbit Monoclonal
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纯化方法
- Protein A affinity chromatography
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免疫原
- Full-length human recombinant protein was used as the immunogen for the recombinant p63 antibody.
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亚型
- IgG, kappa
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应用备注
- The stated application concentrations are suggested starting points. Titration of the recombinant p63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the recombinant p63 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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别名
- p63
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背景
- Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. [UniProt]
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UniProt
- Q9H3D4
抗原
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