SMNDC1 抗体 (full length)
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北京 101111
Quick Overview for SMNDC1 抗体 (full length) (ABIN7879099)
抗原
See all SMNDC1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- SMNDC1 Antibody (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- Recombinant full-length human SMNDC1 protein was used as the immunogen for the SMNDC1 antibody.
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亚型
- IgG2b
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anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) (AA 1-238) antibody
SMNDC1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) antibodySMNDC1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) antibodySMNDC1 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal PCRP-SMNDC1-1A9 unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) (AA 1-238) antibodySMNDC1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B9 unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) (AA 1-238) antibodySMNDC1 适用: 人 ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) (AA 1-238) antibodySMNDC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) (AA 11-41), (N-Term) antibodySMNDC1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB17335 unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) antibodySMNDC1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) (C-Term) antibodySMNDC1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Survival Motor Neuron Domain Containing 1 (SMNDC1) (C-Term) antibodySMNDC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 山羊, 马, 小鸡, Pig, 非洲爪蟾, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SMNDC1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the SMNDC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SMNDC1 (Survival Motor Neuron Domain Containing 1 (SMNDC1))
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别名
- SMNDC1
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背景
- SPF30 (survival of motor neuron-related-splicing factor 30), also known as SMNDC1 (survival motor neuron domain containing 1) or SMNR (SMN-related protein), is an essential splicing factor required for spliceosome assembly that belongs to the SMN family. It contains one Tudor domain with significant similarity to SMN (survival motor neuron) and is expressed in skeletal muscle, pancreas and heart, localizing to Cajal bodies and nuclear speckles. SPF30 plays an important role in spliceosome assembly and directly interacts with five U snRNPs. The loss of SPF30 causes spliceosome assembly to arrest at prespliceosomes (A complex). This supports a function for SPF30 in mediating the incorporation/recruitment of U4/U5/U6 tri-snRNP to the prespliceosome. In addition, the overexpression of SPF30 can lead to apoptosis.
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UniProt
- O75940
抗原
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