This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SMNDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of human SMNDC1.
This protein is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This protein is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.