SOX4 抗体 (full length)
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北京 101111
Quick Overview for SOX4 抗体 (full length) (ABIN7879075)
抗原
See all SOX4 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- full length
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原理
- SOX4 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Full length recombinant human protein was used as the immunogen for the SOX4 antibody.
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亚型
- IgG2b, kappa
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anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 54-103) antibody
SOX4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 86-114), (N-Term) antibodySOX4 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB18502 unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (N-Term) antibodySOX4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 山羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 86-114) antibodySOX4 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) antibodySOX4 适用: 人 IHC 宿主: 小鼠 Monoclonal SOX4-2540 unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (N-Term) antibodySOX4 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 45-136) antibodySOX4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) antibodySOX4 适用: 人 ICC, DB 宿主: 小鼠 Monoclonal 154C4a unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 1-60) antibodySOX4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 1-100) antibodySOX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the SOX4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the SOX4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))
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别名
- SOX4
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背景
- SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF-AŽ ²-induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival in vitro and for primary tumor growth and metastasis in vivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.
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UniProt
- Q06945
抗原
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